Remember this cartoon of a biological membrane?  Suppose the cartoon represented a plasma membrane, consider the ways in which the various proteins are organized in association with the membrane and answer the following questions:

A. (15 points) Compare and contrast the likely biosynthetic pathways of proteins numbered 2, 5 and 6.   Diagrams would help!

B. (8 points) Once completely synthesized, how are proteins numbered 1 and 6 likely to be delivered accurately to their appropriate sites of function?  What are the targeting mechanisms?
 
 

C. (5 pts)  How would you test your hypothesis concerning either targeting mechanism?
 
 
 
 
 
 
 D. (6 pts) Suppose the membrane illustrated were part of a lysosomal vesicle, how would your answers to A. and B. above differ, if at all?
 

 
 
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